Associations between ACTN3 and OPPERA pain-related genes in malocclusion
نویسندگان
چکیده
منابع مشابه
Associations between ACTN3 and OPPERA pain-related genes in malocclusion
Background We have investigated an orthognathic surgery population to determine how variation in masticatory muscle gene expression and genotype plays a key role in development of both jaw-deformation malocclusion and temporomandibular joint disorders (TMD). A gene of particular interest is ACTN3 since the common R577X polymorphism results in a-actinin-3 protein loss, reduced myofiber Zdisc str...
متن کاملAssociations between Malocclusion and Oral Health-Related Quality of Life among Mongolian Adolescents
Malocclusion may affect oral health-related quality of life (OHR-QoL), however, the previously detected associations were affected by confounding factors. We hypothesized that there is indeed an association between OHR-QoL and malocclusion and investigated in a population-based study of 420 Mongolian adolescents mean age: 12.6 (standard deviation (SD) = 1.09) years from two secondary schools, l...
متن کاملRelationship between Pain-Related Beliefs and Pain Anxiety with Depression in Patients with Rheumatoid Arthritis
Aims and background: Chronic pain has many emotional and psychological pressures and is a complex psychological experience. The purpose of the study was to investigate the relationship of pain-related beliefs and pain anxiety with depression in patients with rheumatoid arthritis. Materials and methods: It was a descriptive-correlational study thus, among patients with rheumatoid arthritis in E...
متن کاملSodium channel genes in pain-related disorders: phenotype-genotype associations and recommendations for clinical use.
Human studies have firmly implicated voltage-gated sodium channels in human pain disorders, and targeted and massively parallel genomic sequencing is beginning to be used in clinical practice to determine which sodium channel variants are involved. Missense substitutions of SCN9A, the gene encoding sodium channel NaV1.7, SCN10A, the gene encoding sodium channel NaV1.8, and SCN11A, the gene enco...
متن کاملIntroducing Critical Pain-related Genes: A System Biology Approach
Introduction: Pain is valuable in diagnosis and also warning of the patients. Many molecular reagents are introduced which are related to pain. In this research, the pain-related genes are screened to identify the critical ones. Methods: First, the pain-related genes were pulling out from the STRING database, and Cytoscape software was used to make the interactome unit. Then the central genes...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Pain
سال: 2014
ISSN: 1744-8069
DOI: 10.1186/1744-8069-10-s1-p4